Distinct Molecular Trajectories Converge to Induce Naive Pluripotency

Understanding how cell identity transitions occur and whether there are multiple paths between the same beginning and end states are questions of wide interest. Here we show that acquisition of naive pluripotency can follow transcriptionally and mechanistically distinct routes. Starting from post-im...

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Udgivet i:Cell Stem Cell
Main Authors: Stuart, Hannah T., Stirparo, Giuliano G., Lohoff, Tim, Bates, Lawrence E., Kinoshita, Masaki, Lim, Chee Y., Sousa, Elsa J., Maskalenka, Katsiaryna, Radzisheuskaya, Aliaksandra, Malcolm, Andrew A., Alves, Mariana R.P., Lloyd, Rebecca L., Nestorowa, Sonia, Humphreys, Peter, Mansfield, William, Reik, Wolf, Bertone, Paul, Nichols, Jennifer, Göttgens, Berthold, Silva, José C.R.
Format: Artigo
Sprog:Inglês
Udgivet: Cell Press 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731995/
https://ncbi.nlm.nih.gov/pubmed/31422912
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2019.07.009
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