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The safety, pharmacodynamics, and pharmacokinetics of immediate-release formulation containing esomeprazole 20 mg/sodium bicarbonate 800 mg in healthy adult male

BACKGROUND: Esomeprazole is the most effective treatment for acid-related disorders and is widely used with enteric coating due to rapid degradation in the acidic environment. However, the enteric-coated formulation delays absorption and onset of action. To overcome this limitation, an immediate-rel...

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Publicat a:Drug Des Devel Ther
Autors principals: Kim, Dasohm, Park, Min Soo, Yoo, Byung Won, Hong, Taegon, Park, Shin Jung, Kim, Choon Ok
Format: Artigo
Idioma:Inglês
Publicat: Dove 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731969/
https://ncbi.nlm.nih.gov/pubmed/31564831
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/DDDT.S212491
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