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Interaction specificity of clustered protocadherins inferred from sequence covariation and structural analysis
Clustered protocadherins, a large family of paralogous proteins that play important roles in neuronal development, provide an important case study of interaction specificity in a large eukaryotic protein family. A mammalian genome has more than 50 clustered protocadherin isoforms, which have remarka...
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| Udgivet i: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
National Academy of Sciences
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6731663/ https://ncbi.nlm.nih.gov/pubmed/31431536 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1821063116 |
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