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Structure and sequence analyses of clustered protocadherin reveal antiparallel interactions that mediate homophilic specificity
Clustered protocadherin (Pcdh) proteins mediate dendritic self-avoidance in neurons via specific homophilic interactions in their extracellular cadherin (EC) domains. We determined crystal structures of EC1-EC3, containing the homophilic specificity-determining region, of two mouse clustered Pcdh is...
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| Publicado no: | Structure |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4635037/ https://ncbi.nlm.nih.gov/pubmed/26481813 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2015.09.005 |
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