Wnt signaling regulates trans-differentiation of stem cell like type 2 alveolar epithelial cells to type 1 epithelial cells

BACKGROUND: Type 2 alveolar epithelial cells (AT2s) behave as stem cells and show clonal proliferation upon alveolar injury followed by trans-differentiation (TD) into Type 1 alveolar epithelial cells (AT1s). In the present study we identified signaling pathways involved in the physiological AT2-to-...

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Detalles Bibliográficos
Publicado en:Respir Res
Main Authors: Abdelwahab, Elhusseiny Mohamed Mahmud, Rapp, Judit, Feller, Diana, Csongei, Veronika, Pal, Szilard, Bartis, Domokos, Thickett, David R., Pongracz, Judit Erzsebet
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2019
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731587/
https://ncbi.nlm.nih.gov/pubmed/31492143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12931-019-1176-x
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