A Negative Feedback Loop Regulates Integrin Inactivation and Promotes Neutrophil Recruitment to Inflammatory Sites

Neutrophils are abundant circulating leukocytes that are rapidly recruited to sites of inflammation in an integrin-dependent fashion. Contrasting with the well-characterized regulation of integrin activation, mechanisms regulating integrin inactivation remain largely obscure. Using mouse neutrophils...

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Veröffentlicht in:J Immunol
Hauptverfasser: McCormick, Barry, Craig, Helen E., Chu, Julia Y., Carlin, Leo M., Canel, Marta, Wollweber, Florian, Toivakka, Matilda, Michael, Melina, Astier, Anne L., Norton, Laura, Lilja, Johanna, Felton, Jennifer M., Sasaki, Takehiko, Ivaska, Johanna, Hers, Ingeborg, Dransfield, Ian, Rossi, Adriano G., Vermeren, Sonja
Format: Artigo
Sprache:Inglês
Veröffentlicht: AAI 2019
Schlagworte:
Innate Immunity and Inflammation
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731454/
https://ncbi.nlm.nih.gov/pubmed/31427445
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1900443
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