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Blocking integrin inactivation as an anti-angiogenic therapy

During angiogenesis, endothelial cell migration is coordinated by integrin-mediated contact with the extra-cellular matrix (ECM), coupled with receptor tyrosine kinase signalling to regulate dynamic cytoskeletal and plasma membrane reorganization. A recent paper by Vitorino et al (2015) defined a ne...

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Détails bibliographiques
Publié dans:EMBO J
Auteurs principaux: Saharinen, Pipsa, Ivaska, Johanna
Format: Artigo
Langue:Inglês
Publié: John Wiley & Sons, Ltd 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4491991/
https://ncbi.nlm.nih.gov/pubmed/25828097
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embj.201591504
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