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The inhibition of SGK1 suppresses epithelial-mesenchymal transition and promotes renal tubular epithelial cell autophagy in diabetic nephropathy

Diabetic nephropathy (DN) is a common complication of diabetes that is the dominant cause of end-stage renal disease. However, the pathological mechanism of DN is yet to be elucidated. Serum and glucocorticoid induced kinase (SGK) 1, a ubiquitously expressed kinase, was employed in the current study...

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Bibliografske podrobnosti
izdano v:Am J Transl Res
Main Authors: Zhuang, Langen, Jin, Guoxi, Hu, Xiaolei, Yang, Qingqing, Shi, Zhaoming
Format: Artigo
Jezik:Inglês
Izdano: e-Century Publishing Corporation 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731399/
https://ncbi.nlm.nih.gov/pubmed/31497211
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