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Mechanism of centromere recruitment of the CENP-A chaperone HJURP and its implications for centromere licensing
Nucleosomes containing the histone H3 variant CENP-A are the epigenetic mark of centromeres, the kinetochore assembly sites required for chromosome segregation. HJURP is the CENP-A chaperone, which associates with Mis18α, Mis18β, and M18BP1 to target centromeres and deposit new CENP-A. How these pro...
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| Publicado en: | Nat Commun |
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| Autores principales: | , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group UK
2019
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6731319/ https://ncbi.nlm.nih.gov/pubmed/31492860 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-12019-6 |
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