CDK-regulated dimerization of M18BP1 on a Mis18 hexamer is necessary for CENP-A loading

Centromeres are unique chromosomal loci that promote the assembly of kinetochores, macromolecular complexes that bind spindle microtubules during mitosis. In most organisms, centromeres lack defined genetic features. Rather, they are specified epigenetically by a centromere-specific histone H3 varia...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Pan, Dongqing, Klare, Kerstin, Petrovic, Arsen, Take, Annika, Walstein, Kai, Singh, Priyanka, Rondelet, Arnaud, Bird, Alexander W, Musacchio, Andrea
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2017
Assuntos:
Biochemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5245964/
https://ncbi.nlm.nih.gov/pubmed/28059702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.23352
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