Components of genetic associations across 2,138 phenotypes in the UK Biobank highlight adipocyte biology

Population-based biobanks with genomic and dense phenotype data provide opportunities for generating effective therapeutic hypotheses and understanding the genomic role in disease predisposition. To characterize latent components of genetic associations, we apply truncated singular value decompositi...

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Publicado en:Nat Commun
Main Authors: Tanigawa, Yosuke, Li, Jiehan, Justesen, Johanne M., Horn, Heiko, Aguirre, Matthew, DeBoever, Christopher, Chang, Chris, Narasimhan, Balasubramanian, Lage, Kasper, Hastie, Trevor, Park, Chong Y., Bejerano, Gill, Ingelsson, Erik, Rivas, Manuel A.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2019
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731283/
https://ncbi.nlm.nih.gov/pubmed/31492854
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11953-9
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