Small-protein Enrichment Assay Enables the Rapid, Unbiased Analysis of Over 100 Low Abundance Factors from Human Plasma

Unbiased and sensitive quantification of low abundance small proteins in human plasma (e.g. hormones, immune factors, metabolic regulators) remains an unmet need. These small protein factors are typically analyzed individually and using antibodies that can lack specificity. Mass spectrometry (MS)-ba...

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Udgivet i:Mol Cell Proteomics
Main Authors: Harney, Dylan J., Hutchison, Amy T., Su, Zhiduan, Hatchwell, Luke, Heilbronn, Leonie K., Hocking, Samantha, James, David E., Larance, Mark
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Biochemistry and Molecular Biology 2019
Fag:
Technological Innovation and Resources
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731089/
https://ncbi.nlm.nih.gov/pubmed/31308252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/mcp.TIR119.001562
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