Transient crosslinking kinetics optimize gene cluster interactions

Our understanding of how chromosomes structurally organize and dynamically interact has been revolutionized through the lens of long-chain polymer physics. Major protein contributors to chromosome structure and dynamics are condensin and cohesin that stochastically generate loops within and between...

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Udgivet i:PLoS Comput Biol
Main Authors: Walker, Benjamin, Taylor, Dane, Lawrimore, Josh, Hult, Caitlin, Adalsteinsson, David, Bloom, Kerry, Forest, M. Gregory
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2019
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730938/
https://ncbi.nlm.nih.gov/pubmed/31433796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1007124
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