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Entropy gives rise to topologically associating domains

We investigate chromosome organization within the nucleus using polymer models whose formulation is closely guided by experiments in live yeast cells. We employ bead-spring chromosome models together with loop formation within the chains and the presence of nuclear bodies to quantify the extent to w...

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Publicat a:Nucleic Acids Res
Autors principals: Vasquez, Paula A., Hult, Caitlin, Adalsteinsson, David, Lawrimore, Josh, Forest, Mark G., Bloom, Kerry
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937343/
https://ncbi.nlm.nih.gov/pubmed/27257057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw510
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