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Entropy gives rise to topologically associating domains

We investigate chromosome organization within the nucleus using polymer models whose formulation is closely guided by experiments in live yeast cells. We employ bead-spring chromosome models together with loop formation within the chains and the presence of nuclear bodies to quantify the extent to w...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Vasquez, Paula A., Hult, Caitlin, Adalsteinsson, David, Lawrimore, Josh, Forest, Mark G., Bloom, Kerry
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4937343/
https://ncbi.nlm.nih.gov/pubmed/27257057
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw510
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