Protective HLA alleles are associated with reduced LPS levels in acute HIV infection with implications for immune activation and pathogenesis

Despite extensive research on the mechanisms of HLA-mediated immune control of HIV-1 pathogenesis, it is clear that much remains to be discovered, as exemplified by protective HLA alleles like HLA-B*81 which are associated with profound protection from CD4+ T cell decline without robust control of e...

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Bibliographic Details
Published in:PLoS Pathog
Main Authors: Claiborne, Daniel T., Scully, Eileen P., Palmer, Christine D., Prince, Jessica L., Macharia, Gladys N., Kopycinski, Jakub, Michelo, Clive M., Wiener, Howard W., Parker, Rachel, Nganou-Makamdop, Krystelle, Douek, Daniel, Altfeld, Marcus, Gilmour, Jill, Price, Matt A., Tang, Jianming, Kilembe, William, Allen, Susan A., Hunter, Eric
Format: Artigo
Language:Inglês
Published: Public Library of Science 2019
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730937/
https://ncbi.nlm.nih.gov/pubmed/31449552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1007981
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