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Muscle Xenografts Reproduce Key Molecular Features of Facioscapulohumeral Muscular Dystrophy
Aberrant expression of DUX4, a gene unique to humans and primates, causes Facioscapulohumeral Muscular Dystrophy-1 (FSHD), yet the pathogenic mechanism is unknown. As transgenic overexpression models have largely failed to replicate the genetic changes seen in FSHD, many studies of endogenously expr...
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| Publicado no: | Exp Neurol |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6730665/ https://ncbi.nlm.nih.gov/pubmed/31306642 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.expneurol.2019.113011 |
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