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Use of AAV Vectors for CRISPR-Mediated In Vivo Genome Editing in the Retina
Degenerative retinal diseases such as retinitis pigmentosa (RP) and Leber’s congenital amaurosis (LCA) may lead to blindness without effective treatment. With the rapid advancement of the CRISPR/Cas9 genome editing technology, in vivo application of CRISPR/Cas9 holds immense potential for treatment...
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| Publié dans: | Methods Mol Biol |
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| Auteurs principaux: | , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6730636/ https://ncbi.nlm.nih.gov/pubmed/30783971 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-9139-6_7 |
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