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A glycal-based photoaffinity probe that enriches sialic acid binding proteins
To identify sialic acid binding proteins from complex proteomes, three photocrosslinking affinity-based probes were constructed using Neu5Ac (5 and 6) and Neu5Ac2en (7) scaffolds. Kinetic inhibition assays and Western blotting revealed the Neu5Ac2en-based 7 to be an effective probe for the labeling...
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| Udgivet i: | Bioorg Med Chem Lett |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6730559/ https://ncbi.nlm.nih.gov/pubmed/31387789 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2019.07.054 |
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