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A Single Infusion of Brain-Derived Neurotrophic Factor into the Ventral Tegmental Area Induces Long-Lasting Potentiation of Cocaine Seeking after Withdrawal

Cocaine addiction in humans is associated with long-term propensity to relapse. Using a rat relapse model, we found that cocaine seeking induced by exposure to cocaine-associated cues progressively increases after withdrawal. This progressive increase is associated with increases in brain-derived ne...

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Publicat a:J Neurosci
Autors principals: Lu, Lin, Dempsey, Jack, Liu, Shirley Y., Bossert, Jennifer M., Shaham, Yavin
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2004
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730465/
https://ncbi.nlm.nih.gov/pubmed/14973246
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.5124-03.2004
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