Friedreich Ataxia Mouse Models with Progressive Cerebellar and Sensory Ataxia Reveal Autophagic Neurodegeneration in Dorsal Root Ganglia

Friedreich ataxia (FRDA), the most common recessive ataxia, is characterized by degeneration of the large sensory neurons of the spinal cord and cardiomyopathy. It is caused by severely reduced levels of frataxin, a mitochondrial protein involved in iron-sulfur cluster (ISC) biosynthesis. Through a...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Simon, Delphine, Seznec, Hervé, Gansmuller, Anne, Carelle, Nadège, Weber, Philipp, Metzger, Daniel, Rustin, Pierre, Koenig, Michel, Puccio, Hélène
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2004
Gaiak:
Neurobiology of Disease
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730414/
https://ncbi.nlm.nih.gov/pubmed/14985441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4549-03.2004
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