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Loss of Kv3.1 Tonotopicity and Alterations in cAMP Response Element-Binding Protein Signaling in Central Auditory Neurons of Hearing Impaired Mice

The promoter for the kv3.1 potassium channel gene is regulated by a Ca(2+)-cAMP responsive element, which binds the transcription factor cAMP response element-binding protein (CREB). Kv3.1 is expressed in a tonotopic gradient within the medial nucleus of the trapezoid body (MNTB) of the auditory bra...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: von Hehn, Christian A. A., Bhattacharjee, Arin, Kaczmarek, Leonard K.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730406/
https://ncbi.nlm.nih.gov/pubmed/14985434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4554-03.2004
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