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Pharmacological modulation of Kv3.1 mitigates auditory midbrain temporal processing deficits following auditory nerve damage

Higher stages of central auditory processing compensate for a loss of cochlear nerve synapses by increasing the gain on remaining afferent inputs, thereby restoring firing rate codes for rudimentary sound features. The benefits of this compensatory plasticity are limited, as the recovery of precise...

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Dettagli Bibliografici
Pubblicato in:Sci Rep
Autori principali: Chambers, Anna R., Pilati, Nadia, Balaram, Pooja, Large, Charles H., Kaczmarek, Leonard K., Polley, Daniel B.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5727503/
https://ncbi.nlm.nih.gov/pubmed/29235497
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-17406-x
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