Apoptosis-Inducing Factor Substitutes for Caspase Executioners in NMDA-Triggered Excitotoxic Neuronal Death

The profound neuroprotection observed in poly(ADP-ribose) polymerase-1 (PARP-1) null mice to ischemic and excitotoxic injury positions PARP-1 as a major mediator of neuronal cell death. We report here that apoptosis-inducing factor (AIF) mediates PARP-1-dependent glutamate excitotoxicity in a caspas...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Neurosci
Päätekijät: Wang, Hongmin, Yu, Seong-Woon, Koh, David W., Lew, Jasmine, Coombs, Carmen, Bowers, William, Federoff, Howard J., Poirier, Guy G., Dawson, Ted M., Dawson, Valina L.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2004
Aiheet:
Neurobiology of Disease
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730219/
https://ncbi.nlm.nih.gov/pubmed/15574746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3461-04.2004
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia