Mapping Netrin Receptor Binding Reveals Domains of Unc5 Regulating Its Tyrosine Phosphorylation

Netrin and its receptors Unc5 and deleted in colorectal carcinoma (DCC) regulate axon guidance and cell migration. We defined domains involved in the interactions between netrin-1, DCC, and Unc5c. We show that Unc5 requires both Ig domains to interact with netrin. DCC binds through the fourth fibron...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Kruger, Robert P., Lee, Jeeyong, Li, Weiquan, Guan, Kun-Liang
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2004
Matèries:
Cellular/Molecular
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730211/
https://ncbi.nlm.nih.gov/pubmed/15574733
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3715-04.2004
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