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Neurogranin/RC3 Enhances Long-Term Potentiation and Learning by Promoting Calcium-Mediated Signaling
In neurons, neurogranin (Ng) binds calmodulin (CaM), and its binding affinity is reduced by increasing Ca(2+), phosphorylation by PKC, or oxidation by oxidants. Ng concentration in the hippocampus of adult mice varied broadly (Ng(+/+), ∼160-370 and Ng(+/-), ∼70-230 pmol/mg); the level in Ng(+/+) mic...
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| 發表在: | J Neurosci |
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| Main Authors: | , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Society for Neuroscience
2004
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6730132/ https://ncbi.nlm.nih.gov/pubmed/15564582 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2213-04.2004 |
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