Neurogranin/RC3 Enhances Long-Term Potentiation and Learning by Promoting Calcium-Mediated Signaling

In neurons, neurogranin (Ng) binds calmodulin (CaM), and its binding affinity is reduced by increasing Ca(2+), phosphorylation by PKC, or oxidation by oxidants. Ng concentration in the hippocampus of adult mice varied broadly (Ng(+/+), ∼160-370 and Ng(+/-), ∼70-230 pmol/mg); the level in Ng(+/+) mic...

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Pubblicato in:J Neurosci
Autori principali: Huang, Kuo-Ping, Huang, Freesia L., Jäger, Tino, Li, Junfa, Reymann, Klaus G., Balschun, Detlef
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2004
Soggetti:
Behavioral/Systems/Cognitive
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730132/
https://ncbi.nlm.nih.gov/pubmed/15564582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2213-04.2004
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