Brain-Derived Neurotrophic Factor Regulation of Retinal Growth Cone Filopodial Dynamics Is Mediated through Actin Depolymerizing Factor/Cofilin

The molecular mechanisms by which neurotrophins regulate growth cone motility are not well understood. This study investigated the signaling involved in transducing BDNF-induced increases of filopodial dynamics. Our results indicate that BDNF regulates filopodial length and number through a Rho kina...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Gehler, Scott, Shaw, Alisa E., Sarmiere, Patrick D., Bamburg, James R., Letourneau, Paul C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Development/Plasticity/Repair
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730129/
https://ncbi.nlm.nih.gov/pubmed/15564592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2836-04.2004
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