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p75 Neurotrophin Receptor Signaling Regulates Growth Cone Filopodial Dynamics through Modulating RhoA Activity

The mechanisms by which neurotrophins regulate growth cone motility are unclear. We investigated the role of the p75 neurotrophin receptor (p75(NTR)) in mediating neurotrophin-induced increases in filopodial length. Our data demonstrate that neurotrophin binding to p75(NTR) is necessary and sufficie...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Gehler, Scott, Gallo, Gianluca, Veien, Eric, Letourneau, Paul C.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729430/
https://ncbi.nlm.nih.gov/pubmed/15128850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0404-04.2004
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