Group I Metabotropic Glutamate Receptor NMDA Receptor Coupling and Signaling Cascade Mediate Spinal Dorsal Horn NMDA Receptor 2B Tyrosine Phosphorylation Associated with Inflammatory Hyperalgesia

Hindpaw inflammation induces tyrosine phosphorylation (tyr-P) of the NMDA receptor (NMDAR) 2B (NR2B) subunit in the rat spinal dorsal horn that is closely related to the initiation and development of hyperalgesia. Here, we show that in rats with Freund's adjuvant-induced inflammation, the incre...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Guo, Wei, Wei, Feng, Zou, Shiping, Robbins, Meredith T., Sugiyo, Shinichi, Ikeda, Tetsuya, Tu, Jian-Cheng, Worley, Paul F., Dubner, Ronald, Ren, Ke
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Behavioral/Systems/Cognitive
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730074/
https://ncbi.nlm.nih.gov/pubmed/15483135
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3422-04.2004
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