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Block of Long-Term Potentiation by Naturally Secreted and Synthetic Amyloid β-Peptide in Hippocampal Slices Is Mediated via Activation of the Kinases c-Jun N-Terminal Kinase, Cyclin-Dependent Kinase 5, and p38 Mitogen-Activated Protein Kinase as well as Metabotropic Glutamate Receptor Type 5
The mechanisms of action of human synthetic and naturally secreted cell-derived amyloid β-peptide (Aβ)(1–42) on the induction of long-term potentiation (LTP) were investigated in the medial perforant path to dentate granule cell synapses in hippocampal slices. Synthetic and cell-derived Aβ strongly...
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| I publikationen: | J Neurosci |
|---|---|
| Huvudupphovsmän: | , , , , |
| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
Society for Neuroscience
2004
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| Ämnen: | |
| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6730034/ https://ncbi.nlm.nih.gov/pubmed/15056716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1633-03.2004 |
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