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Studies on the Development and Behavior of the Dystrophic Growth Cone, the Hallmark of Regeneration Failure, in an In Vitro Model of the Glial Scar and after Spinal Cord Injury

We have developed a novel in vitro model of the glial scar that mimics the gradient of proteoglycan found in vivo after spinal cord injury. In this model, regenerated axons from adult sensory neurons that extended deeply into the gradient developed bulbous, vacuolated endings that looked remarkably...

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Pubblicato in:J Neurosci
Autori principali: Tom, Veronica J., Steinmetz, Michael P., Miller, Jared H., Doller, Catherine M., Silver, Jerry
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729861/
https://ncbi.nlm.nih.gov/pubmed/15269264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0994-04.2004
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