Chronic Enhancement of the Intrinsic Growth Capacity of Sensory Neurons Combined with the Degradation of Inhibitory Proteoglycans Allows Functional Regeneration of Sensory Axons through the Dorsal Root Entry Zone in the Mammalian Spinal Cord

Peripherally conditioned sensory neurons have an increased capacity to regenerate their central processes. However, even conditioned axons struggle in the presence of a hostile CNS environment. We hypothesized that combining an aggressive conditioning strategy with modification of inhibitory reactiv...

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Foilsithe in:J Neurosci
Main Authors: Steinmetz, Michael P., Horn, Kevin P., Tom, Veronica J., Miller, Jared H., Busch, Sarah A., Nair, Dileep, Silver, Daniel J., Silver, Jerry
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2005
Ábhair:
Development/Plasticity/Repair
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725461/
https://ncbi.nlm.nih.gov/pubmed/16135764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2111-05.2005
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