Chronic Enhancement of the Intrinsic Growth Capacity of Sensory Neurons Combined with the Degradation of Inhibitory Proteoglycans Allows Functional Regeneration of Sensory Axons through the Dorsal Root Entry Zone in the Mammalian Spinal Cord

Peripherally conditioned sensory neurons have an increased capacity to regenerate their central processes. However, even conditioned axons struggle in the presence of a hostile CNS environment. We hypothesized that combining an aggressive conditioning strategy with modification of inhibitory reactiv...

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Bibliografische gegevens
Gepubliceerd in:J Neurosci
Hoofdauteurs: Steinmetz, Michael P., Horn, Kevin P., Tom, Veronica J., Miller, Jared H., Busch, Sarah A., Nair, Dileep, Silver, Daniel J., Silver, Jerry
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Society for Neuroscience 2005
Onderwerpen:
Development/Plasticity/Repair
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725461/
https://ncbi.nlm.nih.gov/pubmed/16135764
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2111-05.2005
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