Contactin Associates with Sodium Channel Na(v)1.3 in Native Tissues and Increases Channel Density at the Cell Surface

The upregulation of voltage-gated sodium channel Na(v)1.3 has been linked to hyperexcitability of axotomized dorsal root ganglion (DRG) neurons, which underlies neuropathic pain. However, factors that regulate delivery of Na(v)1.3 to the cell surface are not known. Contactin/F3, a cell adhesion mole...

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Foilsithe in:J Neurosci
Main Authors: Shah, Bhaval S., Rush, Anthony M., Liu, Shujun, Tyrrell, Lynda, Black, Joel A., Dib-Hajj, Sulayman D., Waxman, Stephen G.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Society for Neuroscience 2004
Ábhair:
Cellular/Molecular
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729770/
https://ncbi.nlm.nih.gov/pubmed/15317864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0322-04.2004
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