Contactin Associates with Sodium Channel Na(v)1.3 in Native Tissues and Increases Channel Density at the Cell Surface

The upregulation of voltage-gated sodium channel Na(v)1.3 has been linked to hyperexcitability of axotomized dorsal root ganglion (DRG) neurons, which underlies neuropathic pain. However, factors that regulate delivery of Na(v)1.3 to the cell surface are not known. Contactin/F3, a cell adhesion mole...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Shah, Bhaval S., Rush, Anthony M., Liu, Shujun, Tyrrell, Lynda, Black, Joel A., Dib-Hajj, Sulayman D., Waxman, Stephen G.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2004
Subjects:
Cellular/Molecular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729770/
https://ncbi.nlm.nih.gov/pubmed/15317864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0322-04.2004
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