Contactin Associates with Sodium Channel Na(v)1.3 in Native Tissues and Increases Channel Density at the Cell Surface

The upregulation of voltage-gated sodium channel Na(v)1.3 has been linked to hyperexcitability of axotomized dorsal root ganglion (DRG) neurons, which underlies neuropathic pain. However, factors that regulate delivery of Na(v)1.3 to the cell surface are not known. Contactin/F3, a cell adhesion mole...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Shah, Bhaval S., Rush, Anthony M., Liu, Shujun, Tyrrell, Lynda, Black, Joel A., Dib-Hajj, Sulayman D., Waxman, Stephen G.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729770/
https://ncbi.nlm.nih.gov/pubmed/15317864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0322-04.2004
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