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A single sodium channel mutation produces hyper- or hypoexcitability in different types of neurons
Disease-producing mutations of ion channels are usually characterized as producing hyperexcitability or hypoexcitability. We show here that a single mutation can produce hyperexcitability in one neuronal cell type and hypoexcitability in another neuronal cell type. We studied the functional effects...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2006
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1472458/ https://ncbi.nlm.nih.gov/pubmed/16702558 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0602813103 |
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