Dopamine, through the Extracellular Signal-Regulated Kinase Pathway, Downregulates CD4(+)CD25(+) Regulatory T-Cell Activity: Implications for Neurodegeneration

Fighting off neuronal degeneration requires a well controlled T-cell response against self-antigens residing in sites of the CNS damage. The ability to evoke this response is normally suppressed by naturally occurring CD4(+)CD25(+) regulatory T-cells (Treg). No physiological compound that controls T...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Kipnis, Jonathan, Cardon, Michal, Avidan, Hila, Lewitus, Gil M., Mordechay, Sharon, Rolls, Asya, Shani, Yael, Schwartz, Michal
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2004
Fag:
Development/Plasticity/Repair
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729670/
https://ncbi.nlm.nih.gov/pubmed/15240805
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0600-04.2004
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