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Dual effect of CD4(+)CD25(+) regulatory T cells in neurodegeneration: A dialogue with microglia

Autoimmune CD4(+) T cells can mediate the ability to withstand neurodegenerative conditions. Here we show that the ability to spontaneously manifest a T cell-dependent protective response is restricted by naturally occurring CD4(+)CD25(+) regulatory T cells (Treg); depletion of Treg was beneficial i...

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Detalhes bibliográficos
Main Authors: Kipnis, Jonathan, Avidan, Hila, Caspi, Rachel R., Schwartz, Michal
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC521988/
https://ncbi.nlm.nih.gov/pubmed/15331781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0404842101
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