Dual effect of CD4(+)CD25(+) regulatory T cells in neurodegeneration: A dialogue with microglia
Autoimmune CD4(+) T cells can mediate the ability to withstand neurodegenerative conditions. Here we show that the ability to spontaneously manifest a T cell-dependent protective response is restricted by naturally occurring CD4(+)CD25(+) regulatory T cells (Treg); depletion of Treg was beneficial i...
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| Опубликовано в:: | Proc Natl Acad Sci U S A |
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| Главные авторы: | , , , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
National Academy of Sciences
2004
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC521988/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/15331781/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0404842101 |
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