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Production and Release of Neuroprotective Tumor Necrosis Factor by P2X(7) Receptor-Activated Microglia

After a brain insult, ATP is released from injured cells and activates microglia. The microglia that are activated in this way then release a range of bioactive substances, one of which is tumor necrosis factor (TNF). The release of TNF appears to be dependent on the P2X(7) receptor. The inhibitors...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Suzuki, Tomohisa, Hide, Izumi, Ido, Katsutoshi, Kohsaka, Shinichi, Inoue, Kazuhide, Nakata, Yoshihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2004
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729576/
https://ncbi.nlm.nih.gov/pubmed/14715932
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3792-03.2004
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