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Alternative Splicing as a Molecular Switch for Ca(2+)/Calmodulin-Dependent Facilitation of P/Q-Type Ca(2+) Channels
Alternative splicing of the P/Q-type channel (Ca(V)2.1) promises customization of the computational repertoire of neurons. Here we report that concerted splicing of its main α(1A) subunit, at both an EF-hand-like domain and the channel C terminus, controls the form of Ca(2+)-dependent facilitation (...
Shranjeno v:
| izdano v: | J Neurosci |
|---|---|
| Main Authors: | , , , , , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
Society for Neuroscience
2004
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6729554/ https://ncbi.nlm.nih.gov/pubmed/15254089 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1712-04.2004 |
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