Alternative Splicing as a Molecular Switch for Ca(2+)/Calmodulin-Dependent Facilitation of P/Q-Type Ca(2+) Channels

Alternative splicing of the P/Q-type channel (Ca(V)2.1) promises customization of the computational repertoire of neurons. Here we report that concerted splicing of its main α(1A) subunit, at both an EF-hand-like domain and the channel C terminus, controls the form of Ca(2+)-dependent facilitation (...

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Bibliografiske detaljer
Udgivet i:J Neurosci
Main Authors: Chaudhuri, Dipayan, Chang, Siao-Yun, DeMaria, Carla D., Alvania, Rebecca S., Soong, Tuck Wah, Yue, David T.
Format: Artigo
Sprog:Inglês
Udgivet: Society for Neuroscience 2004
Fag:
Cellular/Molecular
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729554/
https://ncbi.nlm.nih.gov/pubmed/15254089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1712-04.2004
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