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Variability in the Benzodiazepine Response of Serotonin 5-HT(1A) Receptor Null Mice Displaying Anxiety-Like Phenotype: Evidence for Genetic Modifiers in the 5-HT-Mediated Regulation of GABA(A) Receptors

Benzodiazepines (BZs) acting as modulators of GABA(A) receptors (GABA(A)Rs) are an important group of drugs for the treatment of anxiety disorders. However, a large inter-individual variation in BZ sensitivity occurs in the human population with some anxiety disorder patients exhibiting diminished s...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Bailey, Sarah J., Toth, Miklos
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729545/
https://ncbi.nlm.nih.gov/pubmed/15254090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0563-04.2004
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