Block of AMPA Receptor Desensitization by a Point Mutation outside the Ligand-Binding Domain

Desensitization of ionotropic glutamate receptors (GluRs), specifically the AMPA receptor subtype, shapes the postsynaptic response at certain synapses in the brain. All known mechanisms that alter desensitization, either pharmacological or mutational, are associated with the ligand-binding domain....

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Yelshansky, Maria V., Sobolevsky, Alexander I., Jatzke, Claudia, Wollmuth, Lonnie P.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729461/
https://ncbi.nlm.nih.gov/pubmed/15152033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0757-04.2004
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