A Seed for Alzheimer Amyloid in the Brain

A fundamental question about the early pathogenesis of Alzheimer's disease (AD) concerns how toxic aggregates of amyloid β protein (Aβ) are formed from its nontoxic soluble form. We hypothesized previously that GM1 ganglioside-bound Aβ (GAβ) is involved in the process. We now examined this poss...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Hayashi, Hideki, Kimura, Nobuyuki, Yamaguchi, Haruyasu, Hasegawa, Kazuhiro, Yokoseki, Tatsuki, Shibata, Masao, Yamamoto, Naoki, Michikawa, Makoto, Yoshikawa, Yasuhiro, Terao, Keiji, Matsuzaki, Katsumi, Lemere, Cynthia A., Selkoe, Dennis J., Naiki, Hironobu, Yanagisawa, Katsuhiko
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729458/
https://ncbi.nlm.nih.gov/pubmed/15152051
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0861-04.2004
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