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Altered Sodium Channel Expression in Second-Order Spinal Sensory Neurons Contributes to Pain after Peripheral Nerve Injury

Peripheral nerve injury is known to upregulate the rapidly repriming Na(v)1.3 sodium channel within first-order spinal sensory neurons. In this study, we hypothesized that (1) after peripheral nerve injury, second-order dorsal horn neurons abnormally express Na(v)1.3, which (2) contributes to the re...

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Pubblicato in:J Neurosci
Autori principali: Hains, Bryan C., Saab, Carl Y., Klein, Joshua P., Craner, Matthew J., Waxman, Stephen G.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2004
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729453/
https://ncbi.nlm.nih.gov/pubmed/15152043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0300-04.2004
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