Memory Impairment in Aged Primates Is Associated with Focal Death of Cortical Neurons and Atrophy of Subcortical Neurons

Mechanisms of cognitive decline with aging remain primarily unknown. We determined whether localized cell loss occurred in brain regions associated with age-related cognitive decline in primates. On a task requiring the prefrontal cortex, aged monkeys were impaired in maintaining representations in...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:J Neurosci
Prif Awduron: Smith, David E., Rapp, Peter R., McKay, Heather M., Roberts, Jeffrey A., Tuszynski, Mark H.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Society for Neuroscience 2004
Pynciau:
Behavioral/Systems/Cognitive
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729447/
https://ncbi.nlm.nih.gov/pubmed/15128851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4289-03.2004
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