Memory Impairment in Aged Primates Is Associated with Focal Death of Cortical Neurons and Atrophy of Subcortical Neurons

Mechanisms of cognitive decline with aging remain primarily unknown. We determined whether localized cell loss occurred in brain regions associated with age-related cognitive decline in primates. On a task requiring the prefrontal cortex, aged monkeys were impaired in maintaining representations in...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Smith, David E., Rapp, Peter R., McKay, Heather M., Roberts, Jeffrey A., Tuszynski, Mark H.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Behavioral/Systems/Cognitive
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729447/
https://ncbi.nlm.nih.gov/pubmed/15128851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4289-03.2004
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