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Memory Impairment in Aged Primates Is Associated with Focal Death of Cortical Neurons and Atrophy of Subcortical Neurons

Mechanisms of cognitive decline with aging remain primarily unknown. We determined whether localized cell loss occurred in brain regions associated with age-related cognitive decline in primates. On a task requiring the prefrontal cortex, aged monkeys were impaired in maintaining representations in...

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Detaylı Bibliyografya
Yayımlandı:J Neurosci
Asıl Yazarlar: Smith, David E., Rapp, Peter R., McKay, Heather M., Roberts, Jeffrey A., Tuszynski, Mark H.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Society for Neuroscience 2004
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729447/
https://ncbi.nlm.nih.gov/pubmed/15128851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4289-03.2004
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