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Memory Impairment in Aged Primates Is Associated with Focal Death of Cortical Neurons and Atrophy of Subcortical Neurons

Mechanisms of cognitive decline with aging remain primarily unknown. We determined whether localized cell loss occurred in brain regions associated with age-related cognitive decline in primates. On a task requiring the prefrontal cortex, aged monkeys were impaired in maintaining representations in...

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書目詳細資料
發表在:J Neurosci
Main Authors: Smith, David E., Rapp, Peter R., McKay, Heather M., Roberts, Jeffrey A., Tuszynski, Mark H.
格式: Artigo
語言:Inglês
出版: Society for Neuroscience 2004
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729447/
https://ncbi.nlm.nih.gov/pubmed/15128851
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4289-03.2004
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