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TRPM8 Activation by Menthol, Icilin, and Cold Is Differentially Modulated by Intracellular pH

TRPM8 is a nonselective cation channel activated by cold and the cooling compounds menthol and icilin (Peier et al., 2002). Here, we have used electrophysiology and the calcium-sensitive dye Fura-2 to study the effect of pH and interactions between temperature, pH, and the two chemical agonists ment...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Andersson, David A., Chase, Henry W. N., Bevan, Stuart
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729305/
https://ncbi.nlm.nih.gov/pubmed/15190109
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0890-04.2004
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