Acute Treatment with the Antidepressant Fluoxetine Internalizes 5-HT(1A) Autoreceptors and Reduces the In Vivo Binding of the PET Radioligand [(18)F]MPPF in the Nucleus Raphe Dorsalis of Rat

Because 5-HT(1A) receptors located on the soma dendrites of serotonin (5-HT) neurons normally mediate an inhibition of 5-HT firing and release, the desensitization of these autoreceptors is essential for obtaining an enhancement of 5-HT transmission after treatment with 5-HT reuptake inhibitors (SSR...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Riad, Mustapha, Zimmer, Luc, Rbah, Latifa, Watkins, Kenneth C., Hamon, Michel, Descarries, Laurent
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729302/
https://ncbi.nlm.nih.gov/pubmed/15190115
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0950-04.2004
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