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5-HT(1A) autoreceptor levels determine vulnerability to stress and response to antidepressants

Most depressed patients don't respond to their first drug treatment, and the reasons for this treatment resistance remain enigmatic. Human studies implicate a polymorphism in the promoter of the serotonin-1A (5-HT(1A)) receptor gene in increased susceptibility to depression and decreased treatm...

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Detalhes bibliográficos
Main Authors: Richardson-Jones, Jesse W, Craige, Caryne P, Guiard, Bruno P, Stephen, Alisson, Metzger, Kayla L, Kung, Hank F, Gardier, Alain M, Dranovsky, Alex, David, Denis J, Beck, Sheryl G, Hen, René, Leonardo, E David
Formato: Artigo
Idioma:Inglês
Publicado em: 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2941196/
https://ncbi.nlm.nih.gov/pubmed/20152112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2009.12.003
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