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Early Striatal Dendrite Deficits followed by Neuron Loss with Advanced Age in the Absence of Anterograde Cortical Brain-Derived Neurotrophic Factor

Brain-derived neurotrophic factor (BDNF), a member of the neurotrophin family, modulates neuronal survival, differentiation, and synaptic function. Reduced BDNF expression in the cortex caused by mutation of the huntingtin gene has been suggested to play a role in the striatal degeneration observed...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Baquet, Zachary C., Gorski, Jessica A., Jones, Kevin R.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729276/
https://ncbi.nlm.nih.gov/pubmed/15115821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3920-03.2004
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